T
he gastric (or bariatric) weight loss surgery the most common are the gastroplasty and "bypass".The gastroplasty, which consists of a reduction in the size of the stomach by laying a ring stomach, a feeling of fullness early. In the case of this weight loss surgery, diabetes is improving after a person has lost weight.
The surgery "bypass" consists, in addition to a reduction in the size of the stomach, to drift food in the intestine distal (which is far from the stomach before the operation). In this case, a rapid and significant improvement of diabetes occurs well before the weight loss.
Work carried out in mice by researchers french From the University Claude Bernard-Lyon can explain it.
The "bypass" stimulates a synthesis of glucose by the intestine, which lasts between meals. The detection of this glucose activates a signal that is transmitted to the brain. It translates into a loss of sensation of hunger. It improves insulin sensitivity and glycemic control.
This work should contribute to the exploration of new therapeutic strategies, surgical or drug, not only obesity, but perhaps also of diabetes in humans, say the authors.
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